We are pleased to announce our next webinar on COVID-19! On Monday, August 10, Yuting Ma will discuss the impacts of psychological stress on virus-associated immune responses. She will share her insights on how COVID-19 has negatively affected our mental well-being, why this might lead to an increased susceptibility to viral infection, and why stress may influence the efficacy of viral vaccines. Don't miss the opportunity to get new insights on this topic and ask your questions - we are looking forward to seeing you on Monday!
The impacts of psychological stress on virus-associated immune responses: unignorable challenges in the COVID-19 pandemic immunity
Date: August 10, 2020
Time: 11:00 (CEST)
The pandemic outbreak of the highly contagious coronavirus (COVID-19) has become a major threat to our physical health. Simultaneously, the rapid spread of COVID-19 and the resulting countermeasures (particularly lockdowns) are negatively affecting our mental well-being, due to disease progression-induced fear and fatigue, social distancing and isolation, family conflicts during quarantine, supply shortages, unemployment, and mounting financial burdens. Accumulating evidence suggests that stress is associated with an increased susceptibility to, and severity of, viral infection, which can be at least partially explained by systemic changes in anti-viral innate and adaptive immunity, as well as dysregulated inflammatory and autoimmune responses. Furthermore, pandemic-related psychological stress may influence the efficacy of viral vaccines. Thus, deciphering the underlying molecular links between psychological stress and viral infection-associated immune-inflammatory alternations will provide novel insights into the development of optimal therapeutic interventions and prophylactic vaccines.
Yuting Ma's research focus is to decipher how multi-level stress responses (therapy-induced cellular stress responses and environmental stressor-induced psychological stress responses) modulate immune reactions.
With the approaches of systems medicine, she aims to explore how various forms of stress responses and cell death modalities, including autophagy, apoptosis, necroptosis, ER stress, pyroptosis, and ferroptosis, modulate the immunogenicity of cancer cells and the immune contexture within the tumor microenvironment.
The webinar will be moderated by Lilin Ye, pricincipal investigator from the Institute of Immunology at the Third Military Medical University, China. His research mainly focuses on dissecting T cell immune responses to viral infection and cancer.